Longevity
What is SHBG (Sex Hormone Binding Globulin)? Optimal Ranges & Function
Normal Range:10-130 nmol/L
Optimal Range:30-70 nmol/L
What is SHBG (Sex Hormone Binding Globulin)?
A protein produced by the liver that binds to sex hormones (testosterone, estradiol, DHT) and transports them through the bloodstream. It regulates how much 'free' hormone is available for tissues to use.
Why SHBG (Sex Hormone Binding Globulin) Matters
SHBG is a powerful longevity marker reflecting metabolic health and hormone balance. Low SHBG is strongly associated with insulin resistance, type 2 diabetes risk, and metabolic syndrome. Higher SHBG in older adults correlates with better cognitive function and reduced cardiovascular risk.
Symptoms of Low SHBG (Sex Hormone Binding Globulin)
- Insulin resistance
- PCOS symptoms (women)
- Acne and oily skin
- Hair loss
- Increased diabetes risk
- Metabolic syndrome
Symptoms of High SHBG (Sex Hormone Binding Globulin)
- Low free testosterone symptoms
- Fatigue and low libido
- Muscle weakness
- Mood changes
- May indicate hyperthyroidism
Reference Ranges
10 nmol/L130 nmol/L
30
70
Standard Lab Range
BioStack Optimal
| Range Type | Minimum | Maximum | Unit |
|---|---|---|---|
| Normal Range | 10 | 130 | nmol/L |
| Optimal Range | 30 | 70 | nmol/L |
Related Biomarkers
Analyze Your SHBG (Sex Hormone Binding Globulin) Levels
Related Topics:
shbg
sex hormone binding globulin
free testosterone
metabolic health
diabetes risk
longevity