Oxidative Stress
What is 8-OHdG (DNA Oxidation Marker)? Optimal Ranges & Function
Normal Range:2-20 ng/mg creatinine
Optimal Range:2-10 ng/mg creatinine
What is 8-OHdG (DNA Oxidation Marker)?
8-OHdG is a modified nucleoside produced when reactive oxygen species damage DNA. Excreted in urine, it serves as the gold standard biomarker for oxidative DNA damage.
Why 8-OHdG (DNA Oxidation Marker) Matters
8-OHdG directly measures DNA oxidation—one of the primary drivers of aging and cancer. Elevated levels indicate chronic oxidative stress damaging your genetic material. Lower levels are associated with reduced cancer risk, slower aging, and better antioxidant status.
Symptoms of Low 8-OHdG (DNA Oxidation Marker)
- Low is ideal
- Indicates good antioxidant protection
- Healthy DNA repair mechanisms
Symptoms of High 8-OHdG (DNA Oxidation Marker)
- Accelerated biological aging
- Increased cancer risk
- Chronic oxidative stress
- Mitochondrial dysfunction
- Neurodegeneration risk
- Cardiovascular disease risk
Reference Ranges
2 ng/mg creatinine20 ng/mg creatinine
2
10
Standard Lab Range
BioStack Optimal
| Range Type | Minimum | Maximum | Unit |
|---|---|---|---|
| Normal Range | 2 | 20 | ng/mg creatinine |
| Optimal Range | 2 | 10 | ng/mg creatinine |
Related Biomarkers
Analyze Your 8-OHdG (DNA Oxidation Marker) Levels
Related Topics:
8-ohdg
dna oxidation
oxidative stress
aging
cancer risk
antioxidant status